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    • Does the Use of Nutritional Supplements Enhance Fertility and Improve IVF Outcome?

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      If you’re trying to get pregnant, you’ve probably wondered whether commercially available fertility supplements could help you achieve your goal. The answer is complex.

      Here is my take: Nutrition is indeed a vital prerequisite for optimal reproductive function. However, a well-balanced diet that meets food preferences, coupled with modest vitamin, mineral and antioxidant supplementation (as can be found in many prenatal vitamin preparations) should suffice.

      This having been said, conceiving is a delicate process, and eating the right foods is essential to optimize reproductive potential. Indeed, a balanced diet (i.e. a lot of organic and brightly colored foods) will provide most of the nutrients you need. But the truth is that most people do not have a balanced diet and are unwittingly often deficient in important nutrients.

      A balanced diet is one that is rich in good quality protein, low in sugar, salt, caffeine and industrially created trans-fats (trans-fatty acids or partially hydrogenated oils) and soy, uncontaminated by heavy metals, free of nicotine, alcohol and recreational drugs. This is why routine supplementation with the following nutrients could enhance preconception readiness:

        • Folic acid (400 micrograms daily)
      • Vitamins A (2565 IU daily); B6 (6mg -10 mg daily); B12 (12-20 mcg per day); C- (2,000 mg a day for both men and women); E (both sexes should get 150-200U daily)
      • Co-enzyme Q10 (100mg daily )
      • Amino acids such as L-Carnitine (3 grams daily) and L-arginine (1 gram per day )
      • Omega 3 fatty acids (1,000-2,400 mg per day)
      • Minerals, mainly zinc (15mg per day); selenium (70-100mcg per day); iron (up to 20mg per day ); magnesium (400mg per day )

      There are likely to be significant reproductive health benefits (including enhanced fertility and intrauterine development) associated with the use of nutritional supplements. However there are also certain potential pitfalls associated with their use. Some supplements are not as safe as they would seem. For example, excessive intake of fat-soluble vitamins (A, D, E and K) can even be dangerous to your health and may be associated with fetal malformations.

      Additionally, numerous supplements have been found to contain contaminants such as toxic plant materials, heavy metals and even prescription medications that can compromise fetal development. Prior to the passage of the Dietary Supplement Health and Education Act of 1994, supplements (vitamins, minerals, amino acids, and botanicals) were required to demonstrate safety. However, since passage of “the Act”, they are now presumed to be safe until shown otherwise, thus establishing a rather hazardous situation where a typical prenatal vitamin that will provide sufficient vitamins and minerals for a healthy early pregnancy and potentially dangerous supplements can and are being sold in the same store without product liability.

      In summary, maximizing reproductive performance and optimizing outcome following fertility treatment requires a combined strategy involving a balanced diet (rich in protein, low in sugars, soy and trans-fats), modest nutritional supplementation, limiting/avoiding foods and contaminants that can compromise reproductive potential, and adopting disciplined lifestyle modification such as not smoking, reducing stress, minimizing alcohol intake, avoiding nicotine and recreational drug consumption, and getting down to a healthy weight through diet and exercise.

      *It is often beneficial in preparing for natural or assisted conception, to seek the advice of a nutritional counselor. This becomes highly advisable where nutritional deficiencies have been diagnosed by a physician and/or in cases where the patient is over/underweight due to medical-hormonal and/or eating disorders.

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      10 Responses to “Does the Use of Nutritional Supplements Enhance Fertility and Improve IVF Outcome?”

      1. Articia says:

        Dr Sher, is egg white protein a suitable replacement for soy? I have avoided the soy and whey protein powders. Thanks!

      2. In my opinion…Yes it is.

        Geoff Sher

      3. Articia says:

        Awesome! Because I cannot handle the rice protein ;)

      4. ency says:

        How do you feel about Maca supplements?

      5. Laura Jester says:

        Can I diet fairly aggressively prior to a cycle without lowering my chance of conception? I am considering doing a low carb (Lots of vegetables and lean meat but nothing starchy) My goal is to limit my calorie intake to around 1200kcal/day. I will not be doing any vigorous exercise. Just walking. What are your thoughts on this program? My goal is to loose as much as possible prior to the procedure.

        • Geoffrey Sher says:

          All three factors can be operative (age, protocol and yes…in my opinion, even the DHEA. Read up on all these in my blog and also read up on embryo banking of CGH-normal embryos. In my opinion, the latter would be the best approach for you.

          Feel free to call 800-780-7437 to set up a vido confernece call to discuss your case with me.

          Good luck!

          Geoff sher

      6. Laura Jester says:

        Regarding soy, it is the Isoflavones that we are trying to avoid, correct? I have done some research about this. Apparently although soy is the highest in isoflavones, all other legumes contain them too. Has any research been done about exactly how many mgs. of Isoflavones are considered acceptable and LOW? I happen to like legumes. :)

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