Infertility Insights
The Real Meaning of Beta hCG Levels
Certainly the most anticipated lab test in a fertility clinic is a human chorionic gonadotropin (hCG) level. While everyone knows that having a positive beta hCG is the ultimate prize, it is far more difficult to truly understand what the test is really telling you.
First, what does a + hCG test really mean? Here we must differentiate between a urine test and a blood pregnancy test. The only real difference is the sensitivity of the test, meaning how high does the hCG level actually have to be to get detected. On a home pregnancy test, the lowest level routinely detected varies between 20-30 mIU/ml. As these levels are achieved fairly early in pregnancy – in fact by the time the expected period is missed – the levels should be above this detection level.
A blood test, on the other hand, is a more vigorous tool and can detect hCG very accurately as low as 5 mIU/ml. Levels below 5 can be detected, but the accuracy of these evaluations suffers greatly. These levels can be detected even before the missed period, hence their usage in IVF cycles. One thing that must be understood here is that these tests cannot distinguish between hCG created by the pregnancy or that given by injection. One must therefore be careful interpreting levels that have been drawn close to the time of the hCG trigger of ovulation/maturity. Twelve days is generally enough time to allow what was injected to be completely metabolized and cleared.
Second, how high must the beta hCG level be before we can actually expect to see something on ultrasound? Once upon a time, when the world was young and I was fresh out of training, we did primarily abdominal scanning. The hCG level most commensurate with seeing the pregnancy was very high, about 6500 mIU/ml. Since the advent of the trans vaginal probe and the great increase in the ability to see things in the uterus, this “U/S detectable” level decreases to about 1000 mIU/ml. This can be equated to about 6 weeks gestation (remember, we always add two weeks to go all the way back to the start of the cycle, not from the time of implantation).
The hardest question to answer is how fast these levels should increase. A common rule of thumb is that on average they should approximately double every two days. But remember that these are averages. When following such numbers, we must use curves like the one shown above. The only truly abnormal parts of the curve are the upper 2.5% and the lower 2.5%. All the other values strung between these two points are still normal, they are simply more or less than their neighbor. It is the same with hCG levels. If the number is not doubling, that is not a reason to “hang crepe” and panic. It is still most probably normal.
Additionally, the doubling time (time needed for the value to double) also changes as the pregnancy advances, hence you can expect the increase to slow down as you follow it. In fact, once the thresholds for ultrasound detection have been passed, following serial hCG levels does little except overly worry people. Again if I had a nickel for every baby I have held in my arms that did not initially have perfectly doubling hCG levels or for every D & C I have had to perform for a failed pregnancy that was indeed doubling, I would be retired in the South of France reading poetry and eating peeled grapes. At a bottom line, do not hesitate to ask your coordinator or physician about their ideas concerning these levels so you do not unduly worry yourselves.
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i had my hcg levels done at a lab today and it came back as reading 1.9miu/ml? what does that mean
Does not sound good I am afraid!
Sorry!
Geoff Sher
14dpt beta-3000+ & 2 days after beta 6900. Is this too high?
It doubled and that is good. Probably a singleton. I don’t think it is too high!
Geoff Sher
I’ve had 6 betas and my RE doesn’t seem worried, but I am. We saw a very tiny gestational sac at 6w2d (when my beta was 2569) What are your thoughts? Could there still be hope?
Beta#1 @11dp5dt: 93
#2 @14dp5dt: 249 (50 hour doubling)
#3 @17dp5dt: 580 (59 hour doubling)
#4 @21dp5dt: 1235 (88 hour doubling)
#5 @26dp5dt: 2569 (90 hour doubling)
#6 @30dp5dt (today): 4658 (110 hr doubling)
I will be 7w tomorrow. We tried for 2 years and had adopted embryos and I’m just devastated thinking this is doomed.
Frankly, I too am somewhat disturbed by the slowish rise in beta’s. However…only time will tell!
Good luck!
Geoff Sher
I would like to know whether mine is a “chemical pregnancy”/false positive. I had IUI on 23rd Feb and had 10,000 pregnyl shot before IUI. Then I had another 2 rounds of Pregnyl shot 5000 each last was on March 1st. I took HPT last night and turned to be clear positive, this morning also positive. I requested for beta today and result at 1700+ iu/L.
I am not sure as I asked my friend’s opinion (she is obgyn), she said it is too early and maybe caused of pregnyl shots.
I am confused and worried because when I went to the hospital/clinic, they told me that the hsg shot can be clear in 7 days, but accdg to my friend the positive and beta result may be affected by the injections.
The nursing assistant told me no need go for 2nd beta, got the result and its at 1700+. Is there a high chance its a false positive?
Sounds like it could be the real thing. Repeat the beta in 2 days and if it doubles…you should be OK.
Good luck!
Geoff Sher
My HGC levels were 856 at 4 weeks is that mean. Twin pregancy ate singleton . Thanks
Sorry Constance. An hCG reading (especially just one) does not give a hint as to how many.
Good luck!
Geoff Sher
Hi again,
Thanks for the reply from earlier posting. I didn’t go for 2nd beta, but continuously taking HPT. Latest was this morning which is 17days past HCG Trigger shot.
My doctor prescibred me take metformin (3x daily) and duphaston (10mg, 2x a day) for 2wks. My question is how does duphaston and metformin helps during this critical stage (1st trimester) pregnancy?
Not sure it really does…
Geoff Sher
On 3/14 my HCG was 26804 and according to my LMP, I am 6 wks 4 days. On 3/16 my HCG results were 35574…only an increase by 32.7%…should I be concerned or were they high enough before that the doubling will slow down?
I would not be concerned this far along but I would get an US done.
Geoff Sher
Thank you for the response. My first appt is two weeks from today, so I’ll have to patiently wait.
Looking forward to it!
Geoff Sher
I am not sure of my LMP but I went to my OB today and had a vaginal USN done. We couldn’t see much of anything other than what seems to be a thickness in the endometrium
My doc sent me for a beta and the value was 12942. I’m not sure how to feel with it being so high and not being able to see anything?
I would be very concer5ned about the possibility of an ectopic pregnancy. Discuss this with your MD ASAP.
Geoff Sher
I’m worried about my LMP r/t my HCGs. My last three LMPs were 11/22, 12/22, and 1/28. I stopped breastfeeding last Nov. I missed my period in the beginning of March and took a upreg that was positive on 3/14. My HCG on 3/18 was 1662 and on 3/18 it was 2685. On 3/18 we saw a gestational sac on the US. Could I really have ovulated and implanted late? Should I be concerned?
3/18 1662 and 3/20 2685. I’m sorry I’m a nervous wreck. My ob didn’t sound very hopeful.
It is a slight lag in the rise but at this stage it might not exactly rise in 2 days. Repeat the US in a week. Then you should know for sure what is happening.
Good luck!
Geoff Sher
It is feasible.
Geoff Sher
Thank you Dr. Sher. After my beta of 2685 my next beta 2 days later was 4200. Today I’m going in for a US to dx a blighted ovum or healthy pregnancy. I am hoping for good news.
Good luck!
Please let us all know the result!
Geoff Sher
Great news! We saw the baby’s heart beating at 111 and the baby is measuring 5w6d. Thank you for your advice and kind words
Wonderful!
G-d bless!
Geoff Sher
On 3/20 6 weeks prego hcg was 4885 on 3/25 6w5d it was 6985 had us they felt concern over development at 6w5d however got pregnant through IVF I am so worried I have had 3 healthy pregnancies before
Go n and do an ultrasound to evaluate.
Good luck!
Geoff Sher
Had ultra sound that is why they repeated hcg levels should I be concerned or could my egg have inplanted several days later
What did the US show?
Geoff Sher
Time will have to tell!
Geoff Sher
I had my blood drawn late in the evening (around 8 PM) And my hcg was 6000. Ultrasound showed a gestational sac and yolk sac. They said I appeared to be 5 weeks 6 days. I went back for more bloodwork around noon on the 29th and it was only up to 7500. Is this way too slow? I’ve read it slows over 6000 and further along too. Please help! I’ve had 3 losses and no babies still!! Hoping for the best but I’m terrified.
It does slow down in rate of rise, but this is slow. A suggest a repeat US to establish the status of the pregnancy.
Good luck!
Geoff Sher
Hi,
I am so nervous. I was pregnant at the end of last yr with my first child and when we went for a US at 7 weeks there was no heartbeat and I was told I would have to have a D&C which I had on Nov. 20th. Since then I have not had a regular cycle however on 3/25 I took a hpt and it was positive. Went in on 3/26 and hcg was 22 and the did a US and saw nothing(not surprised) went back on 3/27 and hcg was 47, went back on 4/2 and hcg was 491 they did another US and still nothing (again not surprised) went back on 4/3 and hcg was 757 and yesterday 4/4 hcg was 897…..the believe I may be 5w1day. Are these numbers too low or cause for concern? They scheduled my US for next friday 4/12.
Thanks in advance.
You need to wait another 10-14 days and then repeat the ultrasound.
Geoff Sher
Thank you so much. Do my levels look like they are rising well?
They were initially rising reasonably but seem to be plateauing now….Only time will tell.
Good luck!
Geoff Sher
I went to the hospital because I was spoting and they told me that I’m 6 weeks and they can not see the baby the only see the sac. I had 16.000 beta and 48 hours after I had14.900. I am having an abortion?? Or is it possible the that the beta can go up again??
Hard to say because the beta’s don’t necessarily double every 48 hours when the pregnancy advances further along. Also, it is sometimes hard to see the conceptus at 6 weeks.
give it a week and recheck the ultrasound.
Good luck!
Geoff Sher
Hi
We had a five day blasto transfered on 3/27, had our first blood test for HCG levels 9 days post transfer. The HCG came back at 12. Should we prepare for the worst? Thanks
Cheryl
The level is low. Repeat in 2 days and let’s hope for the best!
Good luck!
Geoff Sher
Dear Dr Sher – My hcg at 12 dpd6t was 495, today at 15dpt it is 871. My estrogen is greater than 2000 and prog greater than 40, however taking both estradiol and Prog in oil. I am concerned with this hcg today. Can you let me know your thoughts. Thanks for your time. Beth Ann
Hi Beth Ann,
Sorry for the delay in responding…I plumb missed your posting. This is a slow rise but by now you should know how it is evolving. Please update us.
Geoff Sher
Hi
My beta hcg 14dpEC ( 9dp5dt) was 40!
72 hrs later it was up to 131.1
What do low levels indicade and how bad are these numbers?
Thanks in advance
LS
It is still compatible with a viable pregnancy.
Good luck!
Geoff Sher
Dear Dr.Sher
following the initial beta of 40 at 14dpEC and 131 at 17dpEC we tested again at 21 dpEC ( 5 weeks) – 763 and at 27dp EC (5w+6) – 6040 ( the last one was done a bit earlier than the others but not ridiculously earlier)
Is this still compatible with viable pregnancy?
How does doubling time change once hcg reaches 6000
Indeed…yes!
Good luck!
Geoff Sher
I have a h.o ectopic pregnancy last June . 14 day post ovulation by bhcg was 23 and 72 hours later 30. Repeated another after 48 hrs still waiting. Very anxious!
Hi Jane,
I can understand your consternation.Frankly, this could be a failing pregnancy but only time will tell.
Keep me in the loop please!
Geoff Sher
The repeat b hcg after 48 hrs is only 50. Prog is 13 it was 20 previously and eatrogen levels are high per the ob Gyn . She says its most likely a biochemical pregnancy and does not feel its an ectopic. I am still v concerned regarding an ectopic? Please let me know what you think. Thanks
With the beta that low, the chance of an ectopic rupturing is in my opinion remote!
Good luck!
Geoff Sher!
Thank you fr your prompt reply . My question to u is : do u agree it is going to be a chemical pregnancy? Wht are the chances if this being an ectopic ?
It looks that way.
Geoff Sher
Hi. Thank you for replying.
A repeat bhcg after 48 hrs is 147 ( it’s increased 3 times from last)
I am not sure what to make out of it.
Your input wid be appreciated
Thank you
That is good. Now wait about 10 days and do an ultrasound.
Good luck and G-d bless!
Geoff Sher
Update: 6 week us shows gestational sac and yolk sac. No fetal pole yet . Beta hcg rising but not doubling. It was 925 one week ago and it is 2700 now a week later . What do u think is happening
Hi Dr Sher – saw a gest sac this AM. HCG 1837.
CONGRATULATIONS!!
Geoff Sher
b- hcg after 21 days of hcg 10000 injection shows the value of 576.4 . Is this a reliable one for pregnancy or may it be a false positive? I had a injection on 18 th march and the test shows poaitive on 7 th april.
This is a good value but you need ultrasound confirmation.
Geoff Sher
Hi Doctor,
I had 3 blastocysts transferred on day 5 on 3/26/13. Here are Hcg levels:
13dpt – 237
15dpt – 222
17dpt – 274
21dpt – 563
Estrogen and progesterone levels have been good. I will have another blood test and first ultrasound tomorrow. How these numbers look to you? I know they are not good, but just wanted your insight. This is my second IVF cycle. On first cycle, embryo arrested. I am 41, and have a son conceive naturally at 37.
Hi Blanca,
This is not a regular rise in beta hCG. I am somewhat pessimistic.
Talk to your RE about it.
Geoff Sher
Hi Dr Sher,
My hcg was 16.8 10dp5dt fet, on day 13 went to 58 and now today at 18 days it has come back at 458 – do you think it could be viable?
It was 2 x 3aa donor egg blasts that were put back on the 29th March
Thank you in advance,
God bless,
Tracy.
Could be fine. Do an ultrasound in 10 ndays to see.
Good luck!
Geoff Sher
Thanks Dr Sher – am in Scotland – first date for US I can get is 2nd May – fingers crossed
Good luck!
Geoff Sher
Hello,
Concerned i may have an ectopic or chemical.. What do you think?
4/13- beta 237
4/16 beta 307
4/18 beta 374
I am 4 weeks 6 days! Could possibly see the start of a sac on ultrasound with cysts on both ovaries! Abdominal cramping comparable to menstrual cramps!!
That is a slow rise and of concern. It could be a failing pregnancy and yes…even an ectopic. Be sure to have your RE follow you up carefully with blood tests and serial US examinations.
Good luck!
Geoff Sher
Hi Dr. Sher,
I had a miscarriage 2/14/13 at 6 weeks 4 days (no heartbeat) and a normal period on 3/16. I was charting and expecting to ovulate around CD12 of my cycle (which is usually 26 days), but my chart had me ovulating on April 1. We conceived that day because we got a positive, very faint, one day past the day I expected my period (3/13/13). I went in for HCG and it was 29.8, progesterone is 13.5. I am very concerned this could be another miscarriage. I went in for another blood test today (48 hours later). Is it possible I ovulated even a few more days 5/1/13? I’m hoping that recent miscarriage could delay it a little and also implantation. I’m 39, in very good health, had one successful pregnancy at 18 years old. I’m dreading the test results tomorrow and have read that statistically, I have a 25% chance of a good pregnancy. Thanks for your insight.
It is really hard to predict what will transpire. Unfortunately only time will tell.
Geoff Sher
I had a very short LP in February, my temperature sharply went down at 10dpo, and I started my period the next day (we started progesterone the next cycle). I just looked at my labwork and it looks like my beta was 2. Would that have been considered a chemical pregnancy or a true negative?
That is hard to say as it could be in the error range.
Geoff Sher
Hello Doctor,
I’m very concerned about my beta levels and my doctor doesn’t seem to think there is a problem.
here are my beta levels
#1 4/13/13- 237
#2 4/16/13- 307
#3 4/18/13- 374
I am approx., 5 weeks along & ultrasound has only shown “maybe” the start of a sac! Can you give me your opinion please
This is indeed a slow rise and not very promising I am afraid.
So sorry!
Geoff Sher
Hi! My lmp was on 02/14/13 I menstruate every 6 to 8 weeks. Saw the OB doctor on 4/12 levels of hcg were 17.000. Had an US on 4/15 was told there was a well implanted sac with no fetal heart beat, they repeated the hcg that day and it was 14.000. I feel fine with some nausea, but the doc is not hopeful, he states that a spontaneous abortion mos likely will occur. Today it’s the 19th and still no bleeding.I am going through a difficult time, I’d love your in put. Thanks in advance,
Erica
I wish I could be optimistic for you but alas, I cannot.
This pregnancy will almost certainly be lost.
So sorry!
Geoff Sher
Thank you Dr. Sher
Dr. Sher,
I went into the ER late Wednesday night with some bleeding. I have had very irregular periods my whole life, so my due date calculations are all over the board. I should be somewhere between 5-7wks along. The doctor in the ER did an u/s and saw a gestational sac and yolk and tested hCG levels (2800). He was unconcerned with the bleeding (not too heavy and old blood), but was concerned with the lack of fetal pole. I went back to the clinic today (Friday, about 39-40hrs later) and my hCG was a bit over 4100. U/s revealed a 10mm gestational sac, but no fetal pole. What do you make of all of this?
You should repeat the US in a week and that will be definitive.
Geoff Sher
I have a question about high hcg levels. at 4w6d my hcg was 6025, at 5w1d it was 16000, at 5w2d it was 25000 and then at 6w2d it was 145000! on ultrasound a yolk sac, fetal pole and HR were detected at the 6w2d, baby measured exactly 6w2d as well. Dr says everything is fine and wasnt sure why hcg was so high, however im still nervous something could be wrong bc these levels seem to high. Is there any correlation between levels this high and downs this early? Can this be normal to have one baby with levels this high?
I really think all will be well. I know you and your Dr are concerned about a partial molar pregnancy but I don’t think these levels are indicative.
Good luck!
Geoff Sher
Thank you, she didn’t seem to be worried about molar after the ultrasound and everything looked good. I just read things about hcg levels and downs and wasnt sure if these levels fit and if it mattered this early on.
You are going to be fine.
Enjoy the journey!
Geoff Sher
I used Ovidrel in conjunction with Femara this cycle. 15 days post injection (13 dpo) my Beta was 1791 (4/19). My beta as of this morning (4/22, 16 dpo) is 2932. The RE nurse said the beta looked beautiful but I have my doubts and concerns. They have scheduled me for an US on the 1st and said they have no concerns at this time. Your thoughts? Could my initial HCG draw have had residual Ovidrel trigger still showing up? So nervous. Thank you.
I do not think that this can be explained by an initial continued effect of Ovidrel. It is a slowish rise . Lets wait and see what the US shows.
Good luck!
Geoff Sher
Thank you. The only other thing that may play a factor is the fact that I ovulated 2-3 eggs this month (COH). With that initial high beta, perhaps more than one fertilized originally and not all are continuing? Thoughts? I have had several chemical pregnancies FYI.
Hard to say! Perhaps we should talk via Skype.
Geoff Sher
800-780-7437
I tested positive with hpt on April 15. Had bleeding for 4 days like a period and still testing positive. Had quant on Thurs April 18, beta 14. Had quant Monday April 22, beta 47. Still positive on hpt and lines getting darker. Had a m/c Nov. 2012 at 7w4d. Do you think my numbers are ok or should I be prepared for the worst? I have another test tomorrow for quant and progesterone.
Hi Andrea,
I hope I am wrong but this does not look good. Discuss with your OB.
Geoff Sher
My wife had 2 blastocysts 5 day FET. At 9dp5dt we were at 36. 11dp5dt 48. 14dp 15. And now 2dp 1350. U/S coming soon. Are we out of the woods? Could the transfer just be slow? No chance both took right?
*14dp5dt was 153 not 15
Wow and *20dp5dt was 1350. Typo city!
Responded!
I didn’t see a reply. could you resend please? BTW U/S showed a sack and Beta rose to 3400… crossing my fingers
Hi Ryan…sorry, my slip up.
It is time to have an ultrasound in the next few days. That should be definitive.
good luck and please keep me in the loop.
Geoff Sher
Taking into consideration your corrections in follow-up posts, it could be a healthy implantation.
Good luck!
Geoff Sher
Geoff Sher
Answered.
My HCG was 2,429 at 5w+1d, and it was 7,900 at 5w+5d. This is a doubling time of about 56 hours. The PA was very concerned that the doubling did not occur in 48 hours, and that it most likely is not viable. We will do an ultrasound for viability at 6w+5d. With a doubling time of 56 hours, this seems compatibile with a viable pregnancy at these levels. Do you agree?
I respectfully do not agree. I think you are still in the running for a viable pregnancy.
Geoff Sher
It might still be OK. Do another US in a week or so and that might provide a definitive answer.
Geoff Sher
Hello Doctor,
I would appreciate your opinion on the development of my B-HCG levels…
12/04/13: 3000 (23dpo or 5w2d)
15/04/13: 8000 (26dpo)
17/04/13: 12000 (28dpo)
19/04/13: 18000 (30dpo)
22/04/13: 24000 (33dpo)
24/04/13: 27850 (35dpo or 7w0d)
My Physician is currently not worried with my hormone levels but keeps saying it is too early to perform an US (he originally wanted me to reach a B-HCG level of 100000 before doing the US).
I am now concerned about the slowing doubling rate and wonder if the Progesterone supplements I’m taking could be extending/maintaining a non-viable pregnancy.
In my opinion it is NOT too early to do an ultrasound. WE can usually do so when the level is above 2,000…let alone, 28000. This needs to be done because it will provide an answer for you.
Geoff Sher.
My hcg levels are rising slowly. Such as… they were 2518 on a Saturday and Monday, not quite 48 hours later, they were 3409. I had them redone on a Wednesday they were 4900…. they are rising but not doubling. An ectopic has been ruled out by ultrasound when they saw a gestational sac with a yolk sac in the uterus. I go in for a repeat beta on Monday and an ultrasound following. Its hard to stay calm and not stress during this time. The Dr is a little concerned but not too much, she says going by the books it should double every 48 hours but not every one does and there are women who have slow rising levels who go onto having normal pregnancies… any insight you can give is appreciated.
You need a repeat ultrasound in a week for a definitive answer.
Good luck!
Geoff Sher
I recently had a chemical pregnancy last month and got pregnant immediately. I would be 5 weeks and 4 days today. Three days ago I got my beta reading at 739 and yesterday at 649. The told me they thought it was a blighted ovum…could there be any way for HCG levels to lower and still be a viable pregnancy?
Sadly, this is not very likely Kacie.
So sorry!
Geoff Sher
Hi Dr. Sher,
I got my BFP last week for IVF #1! I am very excited, but I am a little bit worried about the progression of my betas. My RE doesn’t seem at all concerned and did not order additional bloodwork. I have read things all over the web about doubling times, etc and would just like your perspective. My betas are:
11dp3dt: 170
13dp3dt: 308
By my calculations, this is approximately a rise of 81% and a doubling time of ~56 hours. In your opinion, is this still encouraging, or should they have really doubled in 48 hours to be truly viable? Thanks in advance!
Should still be OK, in my opinion!
Geoff Sher
Dr. Sher, I had a FET of a 5 day blast (w/PGD) on 4/19. Today (7dp 5dt) I had my first beta and it was 7. I took a HPT last night that was basically a negative, then this evening I had a very faint line.
My RE is saying that they have never seen a beta of 7 turn into a real, viable pregnancy. Do you agree with this? I have a history of repeated miscarriage (3x in 2009) and I have 1 son who I had through IVF with PGD in 2011.
Isn’t 7dp 5dt really early to draw a conclusion?
I just want to be realistic about my chances here.
I would appreciate any advice you might have.
Thank you.
I have actually seen a beta of <7 become a viable pregnancy. What is more important is that the beta should double and keep doubling every 48 hours or so.
Geoff Sher
Thank you for your response. Is it true, though, that more often than not this does not result in a viable pregnancy?
I am afraid that is so!
Geoff Sher
Beta repeated today (9dp 5dt), and it was 31. Do you have any idea why it would go from being so low to quadrupling over a 48 hour period? Thank you.
Probably just a delayed implantation…now , hopefully taking off. This does happen.
Repeat in 2 days to make sure it keeps rising appropriately.
Good luck!
Geoff Sher
Thank you. Is late implantation in and of itself problematic – i.e., is it an indicator for miscarriage or other problems?
Not necessarily!
Geoff Sher
I should say – ‘late’ meaning where you get a beta of 7 at 7dp 5dt . . . I don’t know when that means that it implanted.
Late or “slow” …no difference.
Geoff Sher
Also – apologies – I just found out that the embryo transfered was a 6 day embryo, not a 7 – so the first beta of 7 was at 7dp 6dt and the second beta was at 9dp 6dt. Not sure whether or not that affects the answer. And sorry for the million questions, my RE is impossible to get a hold of so I am a little going nuts here over this. Thank you.
Hi Dr Sher,
I had a 5 day transfer with a CGH normal embryo on April 16th. My 10p5dt beta was 33 and progesterone was 17. Today’s beta (3 days later) was 147 and progesterone is 22. I go for another beta on Wednesday. Do you think I just had a late implanter?
Thank you!
No! It seems appropriate to me.
Geoff Sher
I’m 9 weeks pregnant and the doctor say the baby and heard the heartbeat but they said my hcg levels are very high than usual, what could be the reason for that??
By what you describe and it being 9 weeks with a normal HB, I do not think it is likely to be a problem.
Good luck!
Geoff Sher
Hi, I’m 13 weeks pregnant and my level of beta hCG is very high – 470.8 ng/mL. Does it necessary mean that something is seriously wrong?
Maya,
Something could be wrong here. You need to discuss with your OB/GYN .
G-d bless!
Geoff Sher
hello Dr.
I’m 26 years old, healthy & it’s 1st pregnancy.
my LMP 2ed march, irregular cycle, at 22th April I went to ob doctor and requsted urine shows weak positive and did u/s but nothing, day after did bHCG it was 319, after 5 days back to doctor also nothing on ultrasound asked me see her after 10 days (8th may), repeated BHCG 30th April it was 7961
now I am very worried
why nothing seen on ultrasound?
thanks Dr
I could not say for sure, but your doctor needs to rule out van ectopic (tubal) pregnancy.
Geoff Sher
thanks a lot doctor.
I will be on touch. .
You are most welcome!
Geoff Sher
hello Dr. Sher.
I went to doctor and did transvaginal ultrasound there is intrauterine pregnancy 4w 4d, thanks to God.
she said everything looks well regular sac and there’s a embryo inside it, and no heartbeat yet.
thanks a lot doctor for you advice. .
You are very welcome!
Good luck!
Geoff Sher
I have been bleeding since the 4th of April. My period was due and it hasn’t stopped since then. Took a pregnancy test before and came back negative.. Went to my ob and got blood work done and my hcg levels was 39. I have had a miscarriage before.. Should I be worried? Again….
Your OB/GYN needs to determine why you are bleeding and have a lingering +ve hCG test.
Good luck!
Geoff Sher
My LMP is 3/19/2013 This is baby 6 for me. I had a BHCG drawn on 4/25/13 My results on 4/26/13 was 1475 I had a second BHCG drawn on 4/29/13 I was given the results today 5/1/2013 and my count was 7400. At my OB appointment we were able to see a gestational sac using an abdominal ultrasound. Is this normal or rising on the slow end? I have concern because my fourth child was born in 2003 and between 2003 and 2009 I miscarried 6 times with no explanation as to why? My fifth child was born in October of 2012 without any complication. I want to feel secure about this pregnancy before we tell family. Any advice would be appreciated and welcomed. Thank you.
No! I think you just have to wait it out. I see no reason why this will not result in a beautiful healthy baby.
Good luck and G-d bless!
Geoff Sher
Thank you. I am being followed up by Fetal Assessment Monday Morning so hopefully a heart beat and healthy baby will be visible. I appreciate your feed back. With that many unexplained miscarriages after four healthy babies I was in agony with worry with my fifth this baby is the same I’m a little worried but have more faith because my fifth went well. I shall keep you posted.
I wish you the best!
Geoff Sher
Hi I see that everyone pretty much has the same question. I am really stressing this hcg thing. I have a daughter that is 6 and just started to try for another. From my caculationd I should be 5w3d and I had a beta come back at 15 which the doctor says is low. I had bleeding all day yesterday and that’s when I took the test. The bleeding has stopped now and I go back tomorrow for the second. I’m just soo stressed thinking about it!! Can it be normal to bleed an entire day have a low beta and continue on to have a healthy pregnancy? Any help is appreciated!!
It is probably not a good sign that the beta is so low.
Sorry!
Geoff Sher
Thank you!
Had IVF w/ 2 embryos after a 3-day transfer, first beta on 10dpt was 39, then 4 days later right before results of 2nd beta, started to have bright red bleeding, and that night, pretty severe cramping(worse than normal), but level came back at 120. So, I go back in 2 days for 3rd beta, expecting the worst and rose to 214. Have to go back again in 2 days for another level, but what is going on? How long do I have to keep waiting for the number to reflect a failed pregnancy if that is indeed what is happening? Still with mild bleeding, no more cramping but decided to stay off my feet for a few days. hCG levels not doing the classic 48-hr doubling but they certainly aren’t bad. I keep being told to wait for the next result, but each result leaves me more confused than the last especially with my symptoms. Any thoughts?
Thanks so much.
Unfortunately Vicky, only time will tell. You need to watch the beta level and in about 10 days do an ultrasound. I am sure that your RE is on top of things.
Good luck!
Geoff Sher
Hello,
On 4/17 I had a 5 day transfer of 2 blastocytes. I tested at home and 7dp5dt was beta #1- result 7, 9dp5dt beta#2- result 26, 12dp5dt beta #3- result 49, 14dp5dt beta #4- result 100. Ultrasound scheduled for Monday, May 6th. Is there any hope for this pregnancy?
The numbers started off low but doubled every +/- 48 hours so yes! I think there is hope!
Good luck!
Geoff Sher
Hello,
I am really confused by the HCG levels on my recent blood test. According the the American Pregancy Assoc, and most other websites, normal early HCG levels are as follows:
4 weeks LMP: 5 – 426 mIU/ml
5 weeks LMP: 18 – 7,340 mIU/ml
6 weeks LMP: 1,080 – 56,500 mIU/ml
According to my lab results, they have the HCG ranges as:
4 weeks 4700-132800
5 weeks 3660-134000
6 weeks 22600-135000
Why are these numbers so different? All measurments say they are mIU/ml. I also don’t understand the drop between 4 & 5 weeks. I am 5 1/2 weeks and my HCG level is 5432.20. My previous pregnancy, which ended in miscarriage, had an HCG level of 167 – which was within range according to the American Pregnancy scale.
I am just trying to understand how this current test is being measured so differently.
Thanks,
Amy
Your results look good to me.
You should go in and have an ultrasound ASAP. The result should be definitive.
Good luck!
Geoff Sher
Hello Dr. I should be about 51/2-6 weeks along. My hcg levels have been doubling fine. Went in on 4/1 for ultrasound and all they could see was the sac. No fetal pole. Hcg level was 12,500 that day. Today (5/3) my hcg level was 16,500. My Doctor does not seem optimistic with any of these results. What is your opinion? The stress is quite unbearable. Thank you for your help!
Sarah
So sorry Sarah…but this could well be a blighted ovum. Consider calling 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Hi Dr. Sher,
I’ve undergone 2 failed fresh IVF cycles. With both cycles, embryo did implant, but then pregnancy failed to 7-8 weeks both times. I was able to get pregnant on my own prior to IVF treatment, but those ended up in miscarriages at 5-6 weeks. I already have a 3-year-old conceived naturally at 37. I am currently 41 (I know I’m in the older age bracket for IVF).
In my last IVF cycle that was started in March ’13, my FSH levels were 4.6 and Estradiol levels at 43 on day 3 of my cycle. I responded well to stim medicines which consisted of Menopur and Follistim in both cycles.
Have never had any reproductive system problems. My cycles are always 28 days, and have never experienced any cramping during my period.
I don’t seem to have any implantation problems, but pregnancies just can’t continue beyond 6-7 weeks. I am wondering if I need to have any further testing such as those done by a Reproductive Immunologist, or is it just the case of plain old eggs. I am healthy with no known medical issues. By the way, my husband’s semen analysis was normal.
Thanks in advance for your response.
Blanca
The cause is either chromosomal egg issues (age related) and/or an occult implantation dysfunction. The former is best dealt with through Staggered IVF with CGH embryo selection and possibly using embryo banking (see below) and the latter through evaluation of those factors that impact implantation…most importantly, immunologic (see below).
Please go to the home page of this blog, http://www.IVFauthority.com. When you get there, look for a “search bar” in the upper right hand corner. Type the following subjects into the bar, click on it and it will take you to all the relevant articles posted there.
1. “An Individualized Approach to Ovarian stimulation” (posted on November 22nd, 2010)
2. “Ovarian Stimulation in IVF: Why is it important to down-regulate LH?”
3. “Agonist/Antagonist Conversion Protocol”
4. “Immunologic Implantation Dysfunction” (posted on May, 10th and on May 16th respectively.
5. “Embryo Implantation………” (Part-1 and Part- 2—-Posted August 2012)
6. “Traveling for IVF from Out of State/Country– The Process at SIRM-Las Vegas” (posted on March, 21st 2012)
7.“A personalized, stepwise approach to IVF at SIRM”; Parts 1 & 2 (posted March, 2012)
8. “IVF success: Factors that influence outcome”
9. “Staggered IVF”
10.“Embryo Banking”
Consider calling 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
if 2 weeks after transfer in an IVF cycle, the result of beta HCG shows negative. should we repeat it again, based on the possibility of late implantation?
No!. If it is negative now…that is it!
So sorry!
Geoff Sher
Hello Dr Sher,
The date of conception is March 21st
At 7w6d, hcg: 65 300
At 8w1d, hcg: 77 150
In between, I’ve had bleeding one night as menstrual period (but I’m not bleeding anymore).
Thank you to give me your opinion.
You need an ultrasound examination to provide definitive confirmation.
Geoff Sher
Thank you for your answer.
Just to give a feedback: I had an ultrasound that showed baby was fine despite of an haematoma… So now I try to take it easy.
Good luck!
Geoff Sher
Hello Dr. Sher.
I have had a previous miscarry over three years ago. In between now and then I have had a healthy baby. Now I am pregnant again. 4 weeks after my last menstrual cycle my hCG levels were at 35, 7 days after that test I went for another one and my levels were at 1200. I am going for another two tests, but I am super stressed. Does this seem like it will be a miscarriage? or is there a possibility for a viable pregnancy?
No Shay,
To the contrary, these are good beta hCG levels.
Good luck!
Geoff Sher
My hcg level was 9.5 10dp5dt, frozen cycle. Should I be concerned?
That is on the low side. The second beta should be more definitive.
Geoff Sher
Hello Dr.Sher.
I’m on my 5 days past ET of Day 5 transfer.Is it common to have cramps after an ET? I have had cramps & headache almost since ET and keep thinking AF is coming any day. I am on progesterone shots daily.
These symptoms are very subjective and have little meaning at this stage.
Geoff Sher
Hi Dr Sher,
I had some bleeding at 7w5 days and had a BhCG taken which was about 56300. 36 hours later it was only 56900. I had an ultrasound at 8w1d which showed a healthy heartbeat and no obvious cause for the bleeding. I am concerned though that the slow rising hCG means that the baby’s development was slowing and the scan was too soon to show whether the baby will actually survive. Is 8 weeks too early for the hCG to plateau?
Thanks,
Emma
Your concerns are probably unfounded. The further you get along, the slower the beta rise will be. Also, the findings at US are positive.
Good luck!
Geoff Sher
Hello Dr Sher,
I am currently 6 weeks pregnant after a previous miscarriage. My doctor will not do an ultrasound any earlier than next week, but in the meantime, here are my HCG’s:
4/29 5 weeks 4484
4/30 5 wk, 1 day 5432 (tests are 26 hrs apart)
5/3 5 wk, 3 days 9788 (tests are 66 hrs apart)
I am also on progesterone supplements because my progesterone is only 16 and my OB likes to see it above 20.
Do my HCG’s seem alarming to you? My doctor is not worried, but everything I’ve read tells me otherwise. Especially since my progesterone is also on the lower side.
Thanks,
Amy
I am not corned. Looks OK to me.
good luck!
Geoff sher
Hi again Dr Sher,
I had another beta test on 5/7 – which is 4 days after the previous test (5/3 – HCG 9788) and my level was only 14000. It went from doubling at a rate of 3.5 days to doubling at a rate of 7.7 days.
Does that seem concerning? I am 6 weeks.
Is it true that the doubling time slows down significantly once you pass 6000 and is that regardless to how far along you are?
Thanks!
Amy
Yes! the doubling time will slow down. i strongly urge you to have an ultrasound to get resolution.
Geoff Sher
I had an ultrasound tonight. There is a heartbeat, but it’s only 109. Is that low for 6 weeks 3 days?
I am afraid so. But only time will tell.
Wait a week and do another ultrasound.
While there is life, there is hope.
Geoff Sher
I’ve had lots of dark spotting and now it seems my doubling is taking a very long time. LMP was 3/10 so I am 8 weeks 3 days now.
Beta on 4/19 was 10K.
On 5/3 it was only 80K.
So…doubling every 112 hours. This seems long.
Would love your opinion as to whether things are progressing or not. US scheduled for soon.
I would get a pelvic ultrasound done ASAP.
Geoff Sher
Just wondering if you suspect a miscarriage or something worse….Thanks for your reply.
I cannot say!
Geoff Sher
Updating: bleeding / spotting is abating. Ultra sound looks great. Fetus has good heartbeat and is right on target for gestational age.
Good news!
Geoff Sher
Second pregnancy. Transferred 2 5-day frozen blasts of good quality on April 26. First beta on 05/06 at 10dp5dt was 174. Second beta today (5/08)at 12dp5dt was 337. Is this considered a good doubling time and do you think things look good?
Looks good to me!
Good luck!
Geoff Sher
I am 5 weeks pregnant. My doctor is concerned about my hcg levels. First one taken a week ago was 78, then 88 2 days later and only 91 yesterday. Had a vaginal U/S yesterday. My doctor is certain that this is not a viable pregnancy and said I should miscarry soon:( I had a chemical pregnancy in Jan. I have a 2year old daughter who was conceived naturally with no problem. Just wanted another opinion.
The causes of chemical pregnancies are those that affect egg/embryo quality as well as those that can adversely affect implantation. Please go to the home page of this blog, http://www.IVFauthority.com. When you get there, look for a “search bar” in the upper right hand corner. Type the following subjects into the bar, click on it and it will take you to all the relevant articles posted there.
1. “An Individualized Approach to Ovarian stimulation” (posted on November 22nd, 2010)
2. “Ovarian Stimulation in IVF: Why is it important to down-regulate LH?”
3. “Agonist/Antagonist Conversion Protocol”
4. “Immunologic Implantation Dysfunction” (posted on May, 10th and on May 16th respectively.
5. “Embryo Implantation………” (Part-1 and Part- 2—-Posted August 2012)
Then, you might wish to call 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Hello! My carrier went through an FET cycle & would like to get your advice on her beta levels. 16.3 9dp5dt … 105 13dp5dt … 220 … 17dp5dt & 506 23dp5dt. I was told by our clinic that our carrier should stop meds & come in on Tuesday for an ultrasound. My clinic said this is either a miscarriage or ectopic. We won’t know for another 4 days, but am looking for your thoughts on this cycle. Thank you!
Respectfully, I personally would have preferred to wait another 2 days and repeat the beta before stopping meds…but this is between you and your RE.
Good luck!
Geoff Sher
Thank you for the quick response! I wonder if I should have her continue “just in case”. I am confused with it all. I know it’s rising, but no where near doubling & very low for how many days past transfer… have you ever seen a healthy/viable pregnancy come from a similar situation? Tank you so much for your time!
*Thank you!
Hi, At 9dp a 5dt, my Hcg level was 23, 2 days later it was 48, and 2 days later it was 113. I have an u/s scheduled a week from next Tues. The nurse said we should be “cautiously optimistic” as these are low levels, although they were encouraged about the 2-day doubling time. What is your opinion on the viability? Isn’t the doubling time the most important thing at this stage? This is our first IFV, I have no problems, husband has very low sperm count, had ICSI. Thank you so much!
It looks promising to me.
Good luck!
Geoff Sher
I forgot to add that my symptoms are nausea and extreme fatique at times. Thanks!
Copy!
Dr. Sher,
First IVF: Nov/Dec 2012, 4 8-cell embryos transferred. hcg level tested to be at 3. Used Crinone once a day.
Second IVF: Apr/May 2013, one 5-day full blast was transferred, our hcg level tested to be at 3. Used PIO, 1 ml dose.
We have three frozen embryos from second IVF. What do you think, our chances will be at FET? What would have gone wrong during the second IVF?
You need to be tested for Implantation dysfunction, in my opinion.
Please go to the home page of this blog, http://www.IVFauthority.com. When you get there, look for a “search bar” in the upper right hand corner. Type the following subjects into the bar, click on it and it will take you to all the relevant articles posted there.
1. “Immunologic Implantation Dysfunction” (posted on May, 10th and on May 16th respectively.
2. “Embryo Implantation………” (Part-1 and Part- 2—-Posted August 2012)
Consider calling 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Hi Dr. Sher,
Our first IVF of 2 blasts resulted in a chemical pg. Our FET of 2 blasts resulted in a miscarriage at 10 weeks, analysis of the fetal tissue showed multiple trisomies.
We just did our 2nd IVF with day 3 microarray PGS. We had 1 normal embryo to transfer on day 5. Our first beta at 7dp5dt came in at 39. Second beta today at 9dp5dt was 140. RE’s office was encouraged with the results and did not order more beta’s, but scheduled me for my first ultrasound at 7 weeks. I asked for another beta due to my history, which I will take next Friday at 16dp5dt. What numbers should I be looking for? Do you think my numbers sound ok thus far? Thank you so much!
Looks encouraging.
Good luck and G-d bless!
Geoff Sher
Thank you Dr. Sher! At 16dp5dt, am I looking for numbers around 1700? Or should it be higher?
I had a beta test three weeks ago and it was 1. Its now ten days past ovulation and its 2,,am i pregnant. If not,,what would cause such an increase?
It is hardly a rise. Repeat in 2 days to see if there is a doubling.
Geoff Sher
At 5w6d my HCG was 10131. 64 hours later it was 11951. That’s only a 1820 increase. Should I be concerned?
I would have another beta-hCG test done and go in for an ultrasound ASAP.
Good luck!
Geoff sher
Hi!
I had a IVF with a 5 day blasto 13 days ago.
I had a BW 2 days ago: beta was 206
And today, beta was 242.
They want me to come in 3 days to have another one.
Is that possible it’ll be increased until then or should I expected a bad news?
Thanks
It could be that this is a chemical pregnancy but it could also be a spontaneous reduction from two implanting embryos to one.
Geoff Sher
Hi I have had FET of 5 day blastocyst, The first test showed all was fine and pregnancy had taken place. 4w4days HCG was good and progesterone was low. 5w4days (today) progesterone up to a good level, but HCG dropped from 75th percentile line to about 67th percentile line. My nurse said this is fine – what are your thoughts? Next bloodtest and scan not for another week…
Not possible to say without repeating the beta hCG in 2 day increments and then for a definitive indication, an ultrasound in a week.
Geoff Sher
Hello,
No concern just curious..
My hCG at 14 dpo was 307.1 – I had it tested again at 17 dpo it was 1148.0.
What would the suddenly high level indicate?
Thank you so much for your time
Looks good to me!
Good luck!
Geoff Sher
Hello! I am a little stressed out right now as I have had 6 miscarriages, 1 sucessful and am pregnant again. Date of last period was March 22, 2013. I went for hcg April 29 results: 1276, May 1 results:1717, May 8th results: 3720. My hcg is progressing quite slowly but doctor doesn’t declare it as failed yet. She sent me for another hcg today (results tomorrow) and if they haven’t doubled will send me for ultrasound to check for ectopic. How bad are these numbers? I should be 7 weeks 3 days today. Thank you!
It is a very slow rise and this concerns me. Yes..it could be an ectopic . However, your history of a recurrent loss makes it imperative to rule out implantation dysfunction. Please go to the home page of this blog, http://www.IVFauthority.com. When you get there, look for a “search bar” in the upper right hand corner. Type the following subjects into the bar, click on it and it will take you to all the relevant articles posted there.
1. “Recurrent Pregnancy Loss”
2. “Immunologic Implantation Dysfunction” (posted on May, 10th and on May 16th respectively.
3. “Embryo Implantation………” (Part-1 and Part- 2—-Posted August 2012)
6. “Traveling for IVF from Out of State/Country– The Process at SIRM-Las Vegas” (posted on March, 21st 2012)
7.“A personalized, stepwise approach to IVF at SIRM”; Parts 1 & 2 (posted March, 2012)
Consider calling 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Dear Dr. Sher,
My first beta (13 days post 5 day transfer of 2 embryos) was 1010. I had blood drawn again today, 72 hours later, and the HCG results were 2135. My doctor is concerned that the HCG is not rising fast enough and that I could have an ectopic pregnancy. What do you think the chances are that this is happening, based on your experience? I am going in for an early ultrasound in two days, so I will know a lot more then. In the meantime, I just wanted to get your opinion because I read your site quite often.
Thanks,
Stephanie
I do not think it is a real problem, but it will take an US to determine.
Geoff Sher
I emailed earlier, but didn’t get an answer so maybe you didn’t get this. Anyway, at my9dp a 5dt, my hcg level was 23, which my doctor thought ws poosibly a chemical pregnancy due to such a low level. i retested 2 days later and level was 50. he hd me come in agin 2 days later and my level was 118. Now they are saying this is very promising and are waiting until an ultrasound in 2 weeks. What is your opinion?
It did start low but the doubling effect does make this still a possibly viable pregnancy.
Good Luck!
Geoff Sher
Hi, so I went to the hospital and I know for a fact my last lmp was 4/8/13, and they measured the baby at 5w6days which by the date I should have been 4 weeks, they told me my hcg level was 400 and something and I would for sure miscarry. So in less than 2 days my hcg went up to 1235, and tomorrow I will get my latest result. They said they even saw a fetal pole and everything, this is crazy to me as this is the same hospital who told me there was a baby in my uterus 2 yrs ago and 2 days later I had an ectopic. I have my actual doc working on this now not the hospital. Any thoughts? sorry its so long.
Wow! Pretty confusing…I would do another US in a week. It should be conclusive then.
Good luck!
Geoff Sher
5/1/13 hcg 9.3
5/3/13 hcg 20.8
5/6/13 hcg 90.8
5/10/13 hcg 174
Now today 5/13/13 hcg 228. According to lmp im 5 wks 5 days i haf a small light and short period on 5/2/13. Should i be concerned? I had a miscarriage in January, dr said hopefully it could be possible i was carrying twins but maybe lost1 bcuz my first pregnancy i had fraternal twins. What is your input? We did an ultrasound 5/10/13 but couldn’t see anything, they said i was still too early.
This does not look very promising, I am afraid.
Geoff Sher
My hcg on 5/10/13 was around midnight tho, so they said that was around my 3rd mark still.
Copy!
Geoff Sher
Hi there
I would be grateful if you could look at my numbers below as I am a little concerned. I have an ultrasound booked for Friday May 17th and just trying to prepare myself for what may lie ahead.
1st beta (05/01/13) – 56 (4w & 4d)
2nd beta (05/07/13) – 304 (5w & 3d)
3rd beta (05/13/13) – 949 (6w & 2d)
Although my numbers are rising they are not quite doubling in the ideal time and seems to be on the low side.
I really look forward to hearing your thoughts.
Thank you
Michelle
The rise is slow.. This might not work out for you. If it doesn’t, call 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Hi,
Many thanks for your reply yesterday. They decided to repeat the test yesterday and it has now jumped to 1638, so I’m remaining hopeful at the moment.
Thanks again for your reply.
Michelle
Copy!
Hi,I had my beta HCG levels done at lab 5 days after icorporation and it come back as 3.9 mlu/ml. what does that mean?
It is too early.
Geoff Sher
Hi,
We did our first round of IVF in April. They transferred 2 embryos (4AA and 4AB) on April 27th. I went in for my first beta blood test on May 9th and the level was 304. I went in for a 2nd blood test on May 13th and the level went down to 295. Is this another chemical pregnancy for me? I go back in tomorrow for another blood test.
I am afraid it does not look good. Consider calling 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail
Geoff Sher
Hi Dr. Sher, my beta at 10dp5dt were 18, 2 days later they were 40, 2 days later 95. Opinion on this being viable? Thanx
It is promising. Good luck!
Geoff Sher
Thank you for the reading Geoff. Hubby and I have been though many of the tests if not all. I can’t remember all the names anymore. What seemed to work with the last pregnancy was that my hubby got diagnosed with low thyroid and within 2 weeks of him getting on the meds, I was pregnant and for once it stuck. I am on progesteron and low dose aspirin 81mg like I have been for the last 3-4 pregnancies. I just got my results from yesterdays blood work and it 4315. So looks like this will be a miscarriage too. I wish I had the financial resources to go through testing in the states but I don’t. I just turned 40 in April and was hoping this one would be ok so I could be done with all this pregnancy stuff once and for all. My age is preventing me from wanting to try again although I feel 20. Not sure what to do anymore. Waiting for the doc to call me back and we’ll see what happens. Thanks for your help.
Hi Lynn,
Give nus a call at 800-780-7437 or 702-699-7437 to arrange a Skype consultation (free of charge to those who reside in the United States or Canada) with me so we can discuss your case in detail.
G-d bless!
Geoff Sher
Hi DR Sher, I had a very bad period- lots of large clots and had HCG test done 4 days after starting period and HCG at that point was 10. Does it look like a bio chemical pregnancy?
Unfortunately this is likely!
Geoff Sher
Thank you DR Sher, I appreciate your reply. My DR was trying to say at 4 weeks pregnant the HCG would be in the thousands but I know this not to be true.
In very early pregnancy, is it better to start with lower hcg levels that are doubling every 2 days, or start with a higher level that is not doubling every 2 days. I guess what i am asking is: are doubling hcgs more important that the actual number? Thanks!
Doubling is the more important!
Geoff Sher
Hello again Dr. Sher, my doc called me with the U/S results and it is not ectopic. She said there is a gestational sac etc but it is dating at a little less than 5 weeks. I am supposed to be 7 weeks according to last period. So she’s not calling it a miscarriage but I am still not hopeful. I guess that happens after so many miscarriages. I will repeat my blood work tomorrow. I have left a message with your office to book a skype session. My sister just happens to live in Las Vegas so who knows.
I am so sorry…this does not look good, but I am glad itvis not an ectopic.
Lets interact soon!
Geoff Sher
Dear Dr.Sher,
I would appreciate your help regarding my beta hcg leves. My last period was on 4/11.
1st hcg (5/10/13): 32
2nd hcg(5/14/13): 69
the numbers are doubling in 4 days instead of 2. What do you thing?
I will have another hcg test on 5/18/13.
Looking forward to hearing your opinion.
Regards from Greece (now the time in Greece is 12:24)
Unfortunately this does not look very good…I hope I turn out to be wrong.
Geoff Sher
Hi, I am 14 weeks pregnant and have just been contacted by the hospital to say my hcg levels are high and they are wanting to do additional scans throughout the pregnancy to check babies growth. I had a letter shortly before telling me I was low risk for the downs syndrome testing (1-2000) but I have read that the two are related. Any info would be great – thanks
If in doubt do an amniocentesis which would be definitive. It would be highly likely to be safe at this stage of pregnancy.
Geoff Sher
Hi Dr. Sher,
Thank you in advance for your time.
A bit worried about my HCG #s.
This is my 2nd round of IVF. 1st failed.
1st HCG: 13
2nd: 19
3rd: 43
4th: 80
told to come back in 5 days. I feel fine, no bleeding or anything.
Is there a chance this could be a viable pregnancy with such low HCG #s?
It depends on the time between each beta. If it was 2 days, then you do have a chance.
Good luck!
Geoff Sher
My ovulation date is calculated on 4/22-4/23. My HCG draw levels are:
5/6. 20.2
5/8. 46.8
5/14. 129.4
My OB’s nurse said it doesn’t look good. They scheduled me for US on 5/31 (if I go that far they said). They ordered re drawing it for once a week.
It does not look good, I am afraid.
So Sorry!
Geoff Sher
Thank you for answering.
You are most welcome Kim!
Geoff Sher
Hi… just want to ask if my beta today says zero then clinic says repeat after two days.. still a chance to be pregnant? Im so desperate…
Yes! You should definitely repeat it. It can rise!
Geoff Sher
Dr Sher –
My beta at 10dp5dt is 69. Seems low to me, although my RE was looking for a number above 50. My question is: we transferred a morula (which had pgd). Could this mean we are truly one day behind?
No ! agree with your RE. As long as it doubles over the next 2 days.
Geoff Sher
Dr Sher-
You are such a great person to respond.
My beta went to 149 from 69 in two days.
Thank you again for your assessment of my RE’s opinion.
That’s great!
Good luck!
Geoff Sher
I got my beta hcg back today and it’s only 20. I believe I am 13 dpo. Doctor’s office said to come back and repeat it in 4 days but that it cannot be officially confirmed as a pregnancy yet. Even though I got a positive on a digital pregnancy test yesterday at 12dpo.
Is this a chemical pregnancy? I’ve already had 2 previous miscarriages at 8 weeks.
Too ear5ly to say…I am afraid. The beta needs to double every 2 days though!
Geoff Sher
Hello dr.S,
I just had my first ivf and I beat the odds conceiving. I was given 14% chance by my dr. Due to age (43 y10m).
I had my hcg done 9 d after 5 d blastocysts (4) transfer and it was 81. My ivf dr. Did not see a point in doing a second beta 48 hrs. Later. I had been pregnant twice before (1 succesful at 35 and 1 1miscarriage at 40) and I had the second beta. So I asked my obgyn for a lab slip and did it in another facility.
The second number came at 129 (48 hours later).
So it doubles exactly every 72 hours. Borderline “norm”.
I suppose I should go back again (tomorrow) and check it in the last lab to see- but now I’m so scarred to know too much! Maybe my ivf dr. Purposefully did not want me to dwell on numbers?
My sons numbers were doubling every 24 hours for comparison. What is your opinion please? As I am too embarrassed to admit to my dr I did this test behind his back.
Thank you!
Ideally it needs to double every 48 hours. Repeat the beta but ultimately it will be the ultrasound in about 10 days that would be definitive.
Good luck!
Geoff Sher
Thank you for your response.
My OBGYN suggested doing the intralipid infusion just in case I could have some immunology problem. (My IVF clinic does not check for any of that- they say it’s very rare!!!) The dr. who recommended it just wrote a short email (he is on vacation) so I would like your opinion on that. At this point I should probably try everything!
My answer is simple. I only treat a specific diagnosed condition. I do not believe i a “shotgun approach”.
Geoff Sher
Hi Dr.S.
I ended up repeating the test and it came back at 288 so it doubles every 42 hours (from 129). The lesson would be not to take tests at different labs… I know I have a long way to go- but I am welcoming this piece of good news! thanks for your help!
Good for you!
Geoff Sher
Hi, I am 33 and had a miscarriage at 6 weeks 4 months ago. I am prego again and my B hcg at 4 week 4 day was only 22. When I repeated the test in 48 hours, It was 76. Is it too low for a viable pregnancy?
If it keeps doubling every 2 days you could still be fine.
Good luck!
Geoff Sher
Thanks. I hope it does.
I am booked for my 1st scan in 10 days. Think I will wait patiently for it instead of going crazy checking B Hcg every 2 days.
Copy!
Geoff Sher
Hi Dr.Sher,
I did an IVF cycle and transfered 2 embryos. Below are my beta numbers…could it be twins? do these numbers look like healthy baby/babies to you?
17dp3dt-1,630
19dp3dt-3,690
24dp3dt-19,237
It probably is a singleton!
G-d bless!
Geoff Sher
Dear Doctor, hi! I had 3 frozen 2day embryos transferred and 14 days later my beta showed 3.5 miU/ml (in the lab’s chart this means negative). My ob said I should stop the meds, but I had no period, so 5 days later I did a new beta and it was 23.21. Two days later, 70,18. But then, 4 days later, it went up to only 90. Then three days later on (yesterday), it went up to 182. Also, I have had pink and then brown and dark brown spotting for 10 days now, but no pain, just light cramping. The US shows nothing, only thick endometrium. Tomorrow, I am scheduled for another beta and US but my doctor is very pesimistic…I would appreciate your opinion! Thank you in advance!!!
It does not look optimal…but only time will tell.
Good luck!
Geoff Sher
Hi Dr. Sher,
I posted last week with my early beta numbers:
7dp5dt: 39
9dp5dt: 140
I had another beta yesterday at 16dp5dt and the results were 2441 (40 hour doubling time). Does this beta look within normal range for 5 weeks? I won’t have my first ultrasound until 7 weeks.
Thank you!
It could be fine…Have an ultrasound done i 10 days and that will be definitive.
Good luck!
Geoff Sher
Hello Doc!
Yesterday i did my Beta HCG test and result was 10.01 mIU/mL and today i also got periods..(periods date is 4 days above)What does it means? Can you please ellaborate?
Thanks much.
I am afraid… this is probably not a good sign.
Geoff Sher
Hi doctor,
I had a MMC at 9+ weeks in February! I started clomid April, on the 25th April my BBT chart said I ovulated. I’m concerned about my low rising hcg that is now doubling every 15 hours
Beta:
10/5 HCG 17 @15dpo
13/5 HCG 22 @18dpo
15/5 HCG 92 @20dpo
18/5 HCG 725 @23dpo
Doctor has me doing beta every 2&1/2 days
Should I be worried about the slow rise then sudden doubling?
I also think I may have implanted 7 days after as I had a brown discharge @ 15dpo
Doctor won’t give me an ultrasound till my levels reach 2,000
Thanks for any information
It might have been a slow implantation. Give it 10ndays ands then do an ultrasound.
At the same time be on the lookout for the possibility of a tubal (ectopic) pregnancy.
Good Luck!
Geoff Sher
My levels were as follows: 4 weeks 6 days – 392, four days later at 5 weeks 3 days – 4380. At this rate they appear to be doubling every day instead of every two days. Is this concerning?
Looks good…could be a multiple pregnancy!
Good luck!
Geoff Sher
Hello Dr Sher,
I apologize if this is a duplicate post – I tried asking this a few days ago, but I don’t know if my question went through.
Does non doubling HCG still indicate a likely miscarriage even after the heartbeat is seen on Ultrasound?
My HCG was measured during my 5th week of pregnancy. The first 2 draws doubled at the rate of 3.5 days, but the final 2 doubled at a rate of 8.5 days – they were 9700 & 14000 by that point, but I was still less than 6 weeks along.
My ultrasounds measured 6.0 weeks – heartbeat 109, and 6.4 weeks – heartbeat 127.
My doctors are still treating this as a threatened miscarriage. Do the HCG’s still mean there is something wrong even though development seems to be on track?
Thanks!
I wanted to add, that the 9700 & 14000 were taken 5 days apart, not the normal 2 days…
Copy!
The levels do not keep doubling indefinitely. However, only serial ultrasound examinations done weekly will answer the question as to whether this is going to be a viable pregnancy.
Good luck!
Geoff Sher
Hello Dr. Sher,
I’m struggling with understanding the whole HCG level during pregnancy…what is good…what is not. There are a lot of charts out there with very different ranges.
On 4/28 I took a pregnancy test which yielded a very faint positive. I retested with a digital test which yielded ‘positive’. On 4/29 I went to see my PCP who did blood work. I am on Synthroid because I have a hypothyroid. Later that day I went to my GYN – their strips did not register a ‘positive’.
4/29 HCG 34
5/1 HCG 81
5/20 HCG 5000 with sonogram showing gestational sac.
Any hope for me?
Thanks,
Samantha
There is always hope…but the rise in hCG has tailed off since the 2nd to last beta hCG. An ultrasound a week from now should be more indicative.
Good luck!
Geoff Sher
Hi dr,
My hcg levels are
14dp2dt I.e. 9/5 – 51
11/5- 84
13/5-191
15/5-409
22/5-6622
I went for us on 21/5 which is 6weeks(my lmp was 9/4) and we could see one properly placed 8mm gestational sac with yolk sac. We also found two more gestational sacs at lower side one measuring 3 mm and another 8mm one. Both of these were empty. I was also having pink and brown minor spotting since 19 th night. What are my chances
This probably explains the initial slow rise . You started with a multiple gestation which is reducing. As to the 1 sac…6 weeks is a little early to get a clear sign of a viable pregnancy. Give it another wek or so.
Geoff Sher
Hello dr,
Thanks for ur reply. I have been taking progynova 2 mg which is estradiol valerate 4 times a day. I skipped one dose. My spotting increased a bit and I noticed one clot also. Although its still brown blood. What shall I do? Shall I take another dose in four hours instead of six hour gap and try to fit in missed dose? Making it 5-9-2-8-1 timing of five dose instead of 7-1-7-1 timing of four regular doses? The dose I missed today was of 7 in evening and its already one in night. So already time for next dose. Please help I m scared.
I do not prescribe estradiol valerate in this way so i cannot advise. Contact your RE for his/her input.
Geoff Sher
Hi-I had an u/s and no fetal pole was discovered (9w1d according to doc); I have a tilted uterus, so have requested an appointment with radiology. Unfortunately, seems my levels dropped this morning 19000, 22000, 33000, 31000 as of today. Is there a point in having the u/s now, should I accept this is in fact a pending miscarriage
So sorry…but it sounds quite pointless to re-test. I would suggest a D&C followed by chromosomal evaluation of the products.
Sincerely,
Geoff Sher
Hi Dr. I have a history of 3 chemical pregnancies, 3 failed iuis. I have 1 child 4 years old naturally. I took 2 months off of clomid and am now 18 dpo with HCG of 166, 48 hours before this it was 117.5. I’m on crinone and lovenox. How likely is this pregnancy a chemical as well. I’m will have a third HCG level in another 48 hours.
The levels seem to be lagging. I am afraid this could be a failing implantation.
Geoff Sher
Hi Dr Sher
I am concerned about my slow rising hcg levels. I had a misscarriage 4 months ago so on the edge with this one.
My lmp was 16th April ’13 – here are my hcg results:
20th May (approx 4weeks 6 days) taken at 3pm: 5,880
22nd May (approx 5 weeks 1 day) taken at 8am: 7,100 so not quite 24 hours but a long way off doubling .
Do these numbers look concerning to you?
Thank you so much
Heather
Yes! It is somewhat concerning but at this stage the US picture is the most relevant. Get one done ASAP.
Geoff Sher
Beta was 7065 27 days past ovulation and 96 hours later it was only 9000.I was told not to worry but I am. Any chance?
It is concerning but at this stage the US development is most important,
Geoff Sher
Hello,
I had my trigger shot 5/13 and they did a beta test may 21 and my hgc read 2.5. i was testing out my trigger shot and that morning of the beta result i got my first negative. the RE said that 2.5 is too low to detect on a test for real pregnancy and we will do the real test may 30th. unlike the last time i triggered i had not symptoms ( swollen boobs) and last time i felt ovulation this time i only had three days of cramps. i am still feeling a dull cramp in my left ovary. my follie was a 24 when triggered buy my estrogen level was 78. how does this sound?
Unfortunately these symptoms are too subjective to allow for any deductions.
Geoff Sher
Thank you. Yesterday was my first official prenatal exam (every other office visit was only for U/S or blood work) and my Doctor said that these non doubling levels can also indicate a chromosomal abnormality, which is why I’m under close watch.
In your experience, do non doubling HCG levels result in greater chance of a baby being born with a trisomy?
I suddenly feel like I have so much more to worry about now than just a miscarriage….
Thank you again for all of your input!
It could be an indicator…but not invariably so.
Geoff sher
My first beta was when I believe I was 25 days or so past ovulaton and was 7065. I had anothe beta done 96 hours later and it was only 9000. I know they can rise slowly after the level reaches 6000 but is there any hope? I cant get an ultrasound right away as they are back logged so it could be a week or even 2
Sorry I posted my question twice and didnt realize it
Hi Dr. Sher,
Question about my stats:
9pd5dt: Beta=77
11dp5dt: Beta=171 (41 hr doubling time)
18dp5dt (5wks2dys): Beta=1358 (56 hr doubling time) Only gest sac seen, measured small at 5wks instead of 5wks2days
24dp5dt (6wks1dy): Beta=4361 (86 hr doubling time) Gest AND yolk sac both seen, but still measured around 5 weeks, although there was small growth from last week. No fetal pole seen
Does this progression seem too slow? My beta is rising, slowly, but the sac doesn’t seem to be getting much bigger. And they still weren’t able to see the fetal pole at 6wks1day. The RE was not sure why it was so slow and said all we can do is watch and retest in a week. But I want to know what my chances are.
Unfortunately, the progression is slow. In time you will be able to get a definite indication of where this pregnancy is headed…but to me it does not look very promising…..Sorry!
Geoff Sher
LMP 4/6/14. Negative HPT 4/25 and positive on 4/27. First pregnancy. My betas have been:
4/29. 82 (3 week 2 day)
4/30. 132 (3 weeks 3 day)
5/2. 245 (3 week 5 day)
5/6. 1116 (4 week 2 day)
5/16. 16,981 (5 week 5 days)
I was initially concerned because they seemed higher than the “normal” range. Had 1st ultrasound on 5/23. Should be 6 week 5 days. Saw gestational sac, yolk sac, fetal pole,. No heartbeat. Ultrasound tech dated me at exactly 6 weeks. OB reviewed ultrasound, agreed with the findings, but dated me at 5 weeks. I didn’t think a fetal pole was visible before 6 weeks.
Also, at this point I estimate that my hcg is around 100,000 ( I asked to have it repeated today after the ultrasound and was told he didn’t think it was necessary). Would it be abnormal to have hcg’s this high but no heartbeat?
I strongly advise another Ultrasound ASAP.
Geoff Sher